Technology · PyPI
openbabel (PyPI) vulnerabilities
Updated . Rebuilt every hour.
Junglewise Threat Intelligence has tracked 48 vulnerabilities in openbabel (PyPI): 0 in the last 7 days and 23 in the last 90 days, 12 of them critical and 0 exploited in the wild. The most recent, CVE-2022-46292, was published on 6 July 2026.
- Last 7 days
- 0
- Last 90 days
- 23
- Critical, all time
- 12
- Exploited in the wild
- 0
About openbabel (PyPI)
The Python bindings for Open Babel, a chemical toolbox designed to speak the many languages of chemical data.
Latest openbabel (PyPI) vulnerabilities
- CVE-2022-46292: Open Babel out-of-bounds write in MOPAC output parserhighCVSS 7.8EPSS 0.8%
- CVE-2022-46295: Open Babel out-of-bounds write in MSI parser translationVectorshighCVSS 7.8EPSS 0.9%
- CVE-2022-46294: Open Babel out-of-bounds write in MOPAC input parserhighCVSS 7.8EPSS 0.9%
- CVE-2022-46293: Open Babel out-of-bounds write in MOPAC output parserhighCVSS 7.8EPSS 0.9%
- CVE-2022-46291: Open Babel out-of-bounds write in Gaussian translationVectorshighCVSS 7.8EPSS 0.8%
- CVE-2022-46290: Open Babel heap buffer overflow in ORCA nAtoms parserhighCVSS 7.8EPSS 0.8%
- CVE-2022-46289: Open Babel out-of-bounds write in ORCA nAtoms parserhighCVSS 7.8EPSS 0.8%
- CVE-2022-46280: Open Babel uninitialized pointer dereference in PQS parserhighCVSS 7.8EPSS 0.8%
- CVE-2022-44451: Open Babel uninitialized pointer dereference in MSI atom parserhighCVSS 7.8EPSS 0.8%
- CVE-2022-43607: Open Babel out-of-bounds write in MOL2 attribute/value parserhighCVSS 7.8EPSS 0.8%
- CVE-2022-43467: Open Babel out-of-bounds write in PQS coord_file parserhighCVSS 7.8EPSS 0.8%
- CVE-2022-42885: Open Babel uninitialized pointer dereference in GRO residue parserhighCVSS 7.8EPSS 0.8%
- CVE-2022-41793: Open Babel out-of-bounds write in CSR format parserhighCVSS 7.8EPSS 0.8%
- CVE-2022-37331: Open Babel out-of-bounds write in Gaussian orientation parserhighCVSS 7.8EPSS 0.7%
- CVE-2025-11000: Open Babel out-of-bounds read in PQS parser lowerit helpermediumCVSS 4.4EPSS 0.2%
- CVE-2025-10999: Open Babel NULL pointer dereference in CacaoFormat::SetHilderbrandtmediumCVSS 5.5EPSS 0.3%
- CVE-2025-10998: Open Babel NULL pointer dereference in ChemKinFormat parsermediumCVSS 5.5EPSS 0.2%
- CVE-2025-10997: Open Babel heap buffer overflow in ChemKinFormat::CheckSpecieshighCVSS 7.8EPSS 0.3%
- CVE-2025-10996: Open Babel heap buffer overflow in SMILES OBSmilesParser::ParseSmileshighCVSS 7.8EPSS 0.3%
- CVE-2025-10995: Open Babel out-of-bounds write in zipstream decompressionhighCVSS 7.8EPSS 0.3%
- CVE-2025-10994: Open Babel use-after-free in GAMESSOutputFormat::ReadMoleculehighCVSS 7.8EPSS 0.3%
- CVE-2026-3408: Open Babel NULL pointer dereference in CDXML OBAtom::GetExplicitValencemediumCVSS 5.5EPSS 0.7%
- CVE-2026-2705: Open Babel NULL pointer dereference in MOL2 OBAtom::SetFormalChargemediumCVSS 5.5EPSS 0.8%
- Open Babel NULL pointer dereference in CDXML File HandlermediumCVSS 4.3
- Open Babel out-of-bounds read in CIF File HandlermediumCVSS 4.3
Most severe openbabel (PyPI) vulnerabilities
Exploited in the wild first, then by severity and CVSS score.
- Open Babel out-of-bounds write in CSR format PadStringcriticalCVSS 9.8
- Open Babel uninitialized pointer dereference in PQS format parsercriticalCVSS 9.8
- Open Babel uninitialized pointer dereference in GRO residue parsercriticalCVSS 9.8
- Open Babel out-of-bounds write in PQS coord_file parsercriticalCVSS 9.8
- Open Babel out-of-bounds write in ORCA nAtoms parsercriticalCVSS 9.8
- Open Babel out-of-bounds write in translationVectors parsingcriticalCVSS 9.8
- Open Babel out-of-bounds write in ORCA nAtoms parsercriticalCVSS 9.8
- Open Babel out-of-bounds write in MOPAC translationVectors parsingcriticalCVSS 9.8
- Open Babel out-of-bounds write in translationVectors parsingcriticalCVSS 9.8
- Open Babel out-of-bounds write in translationVectors parsingcriticalCVSS 9.8
Vulnerabilities per week
The last 13 weeks, by the week each vulnerability was published.
| Week of | Bar | Vulns | Critical |
|---|---|---|---|
| 29 Jun 2026 | 22 | 0 | |
| 6 Jul 2026 | 1 | 0 | |
| 13 Jul 2026 | 0 | 0 | |
| 20 Jul 2026 | 0 | 0 | |
| 27 Jul 2026 | 0 | 0 | |
| 3 Aug 2026 | 0 | 0 | |
| 10 Aug 2026 | 0 | 0 | |
| 17 Aug 2026 | 0 | 0 | |
| 24 Aug 2026 | 0 | 0 | |
| 31 Aug 2026 | 0 | 0 | |
| 7 Sep 2026 | 0 | 0 | |
| 14 Sep 2026 | 0 | 0 | |
| 21 Sep 2026 | 0 | 0 |
How this is built
Junglewise Threat Intelligence collects vulnerabilities from NVD, GitHub Security Advisories, OSV, the CISA Known Exploited Vulnerabilities catalog, FIRST EPSS and vendor advisories, and matches each one to the technologies and vendors it affects. Dates are the date a vulnerability was published, in UTC.
The pages are rebuilt from the database every hour. Frozen weekly and monthly reports never change once published, so they can be cited.
Use this data
The same data is at https://junglewise.ai/threats/technologies/openbabel.json, for scripts and language models. It is free to reuse under CC BY 4.0 with a link back to this page.
Cite as: Junglewise Threat Intelligence, "openbabel (PyPI) vulnerabilities", https://junglewise.ai/threats/technologies/openbabel, 26 September 2026.