# Openbabel Open Babel vulnerabilities

Source: https://junglewise.ai/threats/technologies/open-babel  
Publisher: Junglewise Threat Intelligence, https://junglewise.ai/threats  
Updated: 9 November 2026, 03:07 UTC. Rebuilt every hour.  
Data: https://junglewise.ai/threats/technologies/open-babel.json  
License: CC BY 4.0 with a link back

Junglewise Threat Intelligence has tracked 34 vulnerabilities in Openbabel Open Babel: 0 in the last 7 days and 0 in the last 90 days, 12 of them critical and 0 exploited in the wild. The most recent, CVE-2022-46292, was published on 6 July 2026.

## Counts

- Last 7 days: 0
- Last 30 days: 0
- Last 90 days: 0
- All time: 34 (12 critical, 0 exploited in the wild)

## About Openbabel Open Babel

Open Babel is a chemical toolbox designed to speak many languages of chemical data.

## Latest Openbabel Open Babel vulnerabilities

- [CVE-2022-46292: Open Babel out-of-bounds write in MOPAC output parser](https://junglewise.ai/threats/cve-2022-46292-open-babel-out-of-bounds-write-in-mopac-output-parser) (high, CVSS 7.8, published 6 Jul 2026)
- [CVE-2022-46295: Open Babel out-of-bounds write in MSI parser translationVectors](https://junglewise.ai/threats/cve-2022-46295-open-babel-out-of-bounds-write-in-msi-parser-translationvectors) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-46293: Open Babel out-of-bounds write in MOPAC output parser](https://junglewise.ai/threats/cve-2022-46293-open-babel-out-of-bounds-write-in-mopac-output-parser) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-46291: Open Babel out-of-bounds write in Gaussian translationVectors](https://junglewise.ai/threats/cve-2022-46291-open-babel-out-of-bounds-write-in-gaussian-translationvectors) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-46290: Open Babel heap buffer overflow in ORCA nAtoms parser](https://junglewise.ai/threats/cve-2022-46290-open-babel-heap-buffer-overflow-in-orca-natoms-parser) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-46289: Open Babel out-of-bounds write in ORCA nAtoms parser](https://junglewise.ai/threats/cve-2022-46289-open-babel-out-of-bounds-write-in-orca-natoms-parser) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-46280: Open Babel uninitialized pointer dereference in PQS parser](https://junglewise.ai/threats/cve-2022-46280-open-babel-uninitialized-pointer-dereference-in-pqs-parser) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-43607: Open Babel out-of-bounds write in MOL2 attribute/value parser](https://junglewise.ai/threats/cve-2022-43607-open-babel-out-of-bounds-write-in-mol2-attribute-value-parser) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-43467: Open Babel out-of-bounds write in PQS coord_file parser](https://junglewise.ai/threats/cve-2022-43467-open-babel-out-of-bounds-write-in-pqs-coord-file-parser) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-42885: Open Babel uninitialized pointer dereference in GRO residue parser](https://junglewise.ai/threats/cve-2022-42885-open-babel-uninitialized-pointer-dereference-in-gro-residue) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-41793: Open Babel out-of-bounds write in CSR format parser](https://junglewise.ai/threats/cve-2022-41793-open-babel-out-of-bounds-write-in-csr-format-parser) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2022-37331: Open Babel out-of-bounds write in Gaussian orientation parser](https://junglewise.ai/threats/cve-2022-37331-open-babel-out-of-bounds-write-in-gaussian-orientation-parser) (high, CVSS 7.8, published 1 Jul 2026)
- [CVE-2025-10999: Open Babel NULL pointer dereference in CacaoFormat::SetHilderbrandt](https://junglewise.ai/threats/cve-2025-10999-open-babel-null-pointer-dereference-in-cacaoformat) (medium, CVSS 5.5, published 1 Jul 2026)
- [CVE-2025-10995: Open Babel out-of-bounds write in zipstream decompression](https://junglewise.ai/threats/cve-2025-10995-open-babel-out-of-bounds-write-in-zipstream-decompression) (high, CVSS 7.8, published 30 Jun 2026)
- [CVE-2025-10994: Open Babel use-after-free in GAMESSOutputFormat::ReadMolecule](https://junglewise.ai/threats/cve-2025-10994-open-babel-use-after-free-in-gamessoutputformat-readmolecule) (high, CVSS 7.8, published 30 Jun 2026)
- [Open Babel out-of-bounds read in MOL2 file handler](https://junglewise.ai/threats/open-babel-out-of-bounds-read-in-mol2-file-handler-8b67b5e6) (low, CVSS 3.1, published 19 Feb 2026)
- [Open Babel out-of-bounds read in CIF transform3d](https://junglewise.ai/threats/open-babel-out-of-bounds-read-in-cif-transform3d-917f633e) (low, CVSS 3.1, published 19 Feb 2026)
- [CVE-2026-2704: Open Babel out-of-bounds read in CIF File Handler](https://junglewise.ai/threats/cve-2026-2704-open-babel-out-of-bounds-read-in-cif-file-handler) (medium, CVSS 4.4, published 19 Feb 2026)
- [Open Babel NULL pointer dereference in ChemKinFormat](https://junglewise.ai/threats/open-babel-null-pointer-dereference-in-chemkinformat-bd76c929) (low, CVSS 3.3, published 26 Sep 2025)
- [Open Babel out-of-bounds write in zipstream underflow](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-zipstream-underflow-cd0c03f6) (medium, CVSS 5.3, published 26 Sep 2025)
- [Open Babel out-of-bounds write in Gaussian orientation parser](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-gaussian-orientation-parser-ea5cd10a) (high, CVSS 7.3, published 21 Jul 2023)
- [Open Babel out-of-bounds write in MOL2 attribute parser](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-mol2-attribute-parser-1d05dcea) (high, CVSS 8.1, published 21 Jul 2023)
- [Open Babel out-of-bounds write in translationVectors parsing](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-translationvectors-parsing-2e43ea56) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel out-of-bounds write in ORCA nAtoms parser](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-orca-natoms-parser-32f02077) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel out-of-bounds write in MOPAC translationVectors parsing](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-mopac-translationvectors-parsing-4c9b24b9) (critical, CVSS 9.8, published 21 Jul 2023)

## Most severe Openbabel Open Babel vulnerabilities

- [Open Babel out-of-bounds write in PQS coord_file parser](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-pqs-coord-file-parser-b8d4f94b) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel out-of-bounds write in CSR format PadString](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-csr-format-padstring-cc65b1a1) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel out-of-bounds write in ORCA nAtoms parser](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-orca-natoms-parser-149023dd) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel uninitialized pointer dereference in PQS format parser](https://junglewise.ai/threats/open-babel-uninitialized-pointer-dereference-in-pqs-format-parser-9accb245) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel out-of-bounds write in ORCA nAtoms parser](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-orca-natoms-parser-32f02077) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel uninitialized pointer dereference in GRO residue parser](https://junglewise.ai/threats/open-babel-uninitialized-pointer-dereference-in-gro-residue-parser-c86e74aa) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel out-of-bounds write in MOPAC translationVectors parsing](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-mopac-translationvectors-parsing-4c9b24b9) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel out-of-bounds write in translationVectors parsing](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-translationvectors-parsing-54d175ce) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel out-of-bounds write in translationVectors parsing](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-translationvectors-parsing-2e43ea56) (critical, CVSS 9.8, published 21 Jul 2023)
- [Open Babel out-of-bounds write in translationVectors parsing](https://junglewise.ai/threats/open-babel-out-of-bounds-write-in-translationvectors-parsing-d3328bb7) (critical, CVSS 9.8, published 21 Jul 2023)

## Vulnerabilities per week

Nothing was published in the last eight weeks.

| Week of | Vulns | Critical | Exploited |
| --- | --- | --- | --- |
| 17 Aug 2026 | 0 | 0 | 0 |
| 24 Aug 2026 | 0 | 0 | 0 |
| 31 Aug 2026 | 0 | 0 | 0 |
| 7 Sep 2026 | 0 | 0 | 0 |
| 14 Sep 2026 | 0 | 0 | 0 |
| 21 Sep 2026 | 0 | 0 | 0 |
| 28 Sep 2026 | 0 | 0 | 0 |
| 5 Oct 2026 | 0 | 0 | 0 |
| 12 Oct 2026 | 0 | 0 | 0 |
| 19 Oct 2026 | 0 | 0 | 0 |
| 26 Oct 2026 | 0 | 0 | 0 |
| 2 Nov 2026 | 0 | 0 | 0 |
| 9 Nov 2026 | 0 | 0 | 0 |

## Sources

NVD, GitHub Security Advisories, OSV, the CISA Known Exploited Vulnerabilities catalog, FIRST EPSS and vendor advisories. Rebuilt every hour. Cite as: Junglewise Threat Intelligence, "Openbabel Open Babel vulnerabilities", https://junglewise.ai/threats/technologies/open-babel, 9 November 2026.