Yes. openmage/magento-lts (Packagist): upgrade to 19.4.22 or later. Junglewise finds every place you run it, drafts the upgrade and applies it once you approve.
Am I affected by CVE-2021-21395?
Check whether you run openmage/magento-lts (Packagist) at an affected version. Junglewise does that check for you around the clock: connect your code, cloud and domains, and it matches new vulnerabilities like this one against what you actually run and tells you when one reaches you.
How to fix
openmage/magento-lts (Packagist): upgrade to 19.4.22 or later