Yes. io.netty:netty-codec-http2 (Maven): upgrade to 4.1.60.Final or later. Junglewise finds every place you run it, drafts the upgrade and applies it once you approve.
Am I affected by CVE-2021-21295?
Check whether you run io.netty:netty (Maven), io.netty:netty-codec-http2 (Maven) or org.jboss.netty:netty (Maven) at an affected version. Junglewise does that check for you around the clock: connect your code, cloud and domains, and it matches new vulnerabilities like this one against what you actually run and tells you when one reaches you.
How to fix
io.netty:netty-codec-http2 (Maven): upgrade to 4.1.60.Final or later
# set io.netty:netty-codec-http2 to 4.1.60.Final in your pom.xml or build.gradle